faculty members
Hubert Hackl
Asst.-Prof. Dr.
Institute of Bioinformatics, Medical University of Innsbruck

More information will be provided after intial double-blind application process.

Students
Links
selected
publications

Charoentong P, Finotello F, Angelova M, Mayer C, Efremova M, Rieder D, Hackl H, Trajanoski Z. Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade. Cell Rep. 2017 Jan 3;18(1):248-262. doi: 10.1016/j.celrep.2016.12.019.

Moschen AR, Gerner RR, Wang J, Klepsch V, Adolph TE, Reider SJ, Hackl H, Pfister A, Schilling J, Moser PL, Kempster SL, Swidsinski A, Orth Höller D, Weiss G, Baines JF, Kaser A, Tilg H. Lipocalin 2 Protects from Inflammation and Tumorigenesis Associated with Gut Microbiota Alterations. Cell Host Microbe. 2016 Apr 13;19(4):455-69. doi: 10.1016/j.chom.2016.03.007.

Hackl H, Charoentong P, Finotello F, Trajanoski Z. Computational genomics tools for dissecting tumour-immune cell interactions. Nat Rev Genet. 2016 Jul 4;17(8):441-58. doi: 10.1038/nrg.2016.67.

Blatzer M, Jukic E, Posch W, Schöpf B, Binder U, Steger M, Blum G, Hackl H, Gnaiger E, Lass-Flörl C, Wilflingseder D. Amphotericin B Resistance in Aspergillus terreus Is Overpowered by Coapplication of Pro-oxidants. Antioxid Redox Signal. 2015 Dec 20;23(18):1424-38. doi: 10.1089/ars.2014.6220.

Hubert Hackl
Asst.-Prof. Dr.
Institute of Bioinformatics, Medical University of Innsbruck

More information will be provided after intial double-blind application process.


selected publications:

Monfort-Lanzas P, Gronauer R, Madersbacher L, Schatz C, Rieder D, Hackl H. MIO: microRNA target analysis system for immuno-oncology. Bioinformatics. 2022 Jul 11;38(14):3665-3667. doi: 10.1093/bioinformatics/btac366.

Duurland CL, Santegoets SJ, Abdulrahman Z, Loof NM, Sturm G, Wesselink TH, Arens R, Boekestijn S, Ehsan I, van Poelgeest MIE, Finotello F, Hackl H, Trajanoski Z, Ten Dijke P, Braud VM, Welters MJP, van der Burg SH. CD161 expression and regulation defines rapidly responding effector CD4+ T cells associated with improved survival in HPV16-associated tumors. J Immunother Cancer. 2022 Jan;10(1):e003995. doi: 10.1136/jitc-2021-003995.

Moosbrugger-Martinz V, Hackl H, Gruber R, Pilecky M, Knabl L, Orth-Höller D, Dubrac S. Initial Evidence of Distinguishable Bacterial and Fungal Dysbiosis in the Skin of Patients with Atopic Dermatitis or Netherton Syndrome. J Invest Dermatol. 2021 Jan;141(1):114-123. doi: 10.1016/j.jid.2020.05.102.

Finotello F, Rieder D, Hackl H, Trajanoski Z. Next-generation computational tools for interrogating cancer immunity. Nat Rev Genet. 2019 Dec;20(12):724-746. doi: 10.1038/s41576-019-0166-7.

Charoentong P, Finotello F, Angelova M, Mayer C, Efremova M, Rieder D, Hackl H, Trajanoski Z. Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade. Cell Rep. 2017 Jan 3;18(1):248-262. doi: 10.1016/j.celrep.2016.12.019.

Moschen AR, Gerner RR, Wang J, Klepsch V, Adolph TE, Reider SJ, Hackl H, Pfister A, Schilling J, Moser PL, Kempster SL, Swidsinski A, Orth Höller D, Weiss G, Baines JF, Kaser A, Tilg H. Lipocalin 2 Protects from Inflammation and Tumorigenesis Associated with Gut Microbiota Alterations. Cell Host Microbe. 2016 Apr 13;19(4):455-69. doi: 10.1016/j.chom.2016.03.007.

Hackl H, Charoentong P, Finotello F, Trajanoski Z. Computational genomics tools for dissecting tumour-immune cell interactions. Nat Rev Genet. 2016 Jul 4;17(8):441-58. doi: 10.1038/nrg.2016.67.

Blatzer M, Jukic E, Posch W, Schöpf B, Binder U, Steger M, Blum G, Hackl H, Gnaiger E, Lass-Flörl C, Wilflingseder D. Amphotericin B Resistance in Aspergillus terreus Is Overpowered by Coapplication of Pro-oxidants. Antioxid Redox Signal. 2015 Dec 20;23(18):1424-38. doi: 10.1089/ars.2014.6220.


students:

links:


contact

PROGRAM SPEAKER

Univ.-Prof. Dr. Michaela Lackner
Medical University of Innsbruck
Schöpfstrasse 41
A-6020 Innsbruck

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This project is funded by MUI and UIBK. Dummy Icons © Julia Solerti, büro54 Nutzungsrechte bei der Medizinischen Universität Innsbruck. Portrait pictures: MUI/Bullock.